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Functional characterization of tissue-specific enhancers in the DLX5/6 locus

Disruption of distaless homeobox 5 and 6 (Dlx5/6) in mice results in brain, craniofacial, genital, ear and limb defects. In humans, chromosomal aberrations in the DLX5/6 region, some of which do not encompass DLX5/6, are associated with split hand/foot malformation 1 (SHFM1) as well as intellectual...

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Detalhes bibliográficos
Main Authors: Birnbaum, Ramon Y., Everman, David B., Murphy, Karl K., Gurrieri, Fiorella, Schwartz, Charles E., Ahituv, Nadav
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529576/
https://ncbi.nlm.nih.gov/pubmed/22914741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds336
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