A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

BACKGROUND: Large-scale annotation efforts have improved our ability to coarsely predict regulatory elements throughout vertebrate genomes. However, it is unclear how complex spatiotemporal patterns of gene expression driven by these elements emerge from the activity of short, transcription factor b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Smith, Robin P, Riesenfeld, Samantha J, Holloway, Alisha K, Li, Qiang, Murphy, Karl K, Feliciano, Natalie M, Orecchia, Lorenzo, Oksenberg, Nir, Pollard, Katherine S, Ahituv, Nadav
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054837/
https://ncbi.nlm.nih.gov/pubmed/23867016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-7-r72
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge