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A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

BACKGROUND: Large-scale annotation efforts have improved our ability to coarsely predict regulatory elements throughout vertebrate genomes. However, it is unclear how complex spatiotemporal patterns of gene expression driven by these elements emerge from the activity of short, transcription factor b...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Smith, Robin P, Riesenfeld, Samantha J, Holloway, Alisha K, Li, Qiang, Murphy, Karl K, Feliciano, Natalie M, Orecchia, Lorenzo, Oksenberg, Nir, Pollard, Katherine S, Ahituv, Nadav
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054837/
https://ncbi.nlm.nih.gov/pubmed/23867016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-7-r72
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