A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

BACKGROUND: Large-scale annotation efforts have improved our ability to coarsely predict regulatory elements throughout vertebrate genomes. However, it is unclear how complex spatiotemporal patterns of gene expression driven by these elements emerge from the activity of short, transcription factor b...

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Autors principals: Smith, Robin P, Riesenfeld, Samantha J, Holloway, Alisha K, Li, Qiang, Murphy, Karl K, Feliciano, Natalie M, Orecchia, Lorenzo, Oksenberg, Nir, Pollard, Katherine S, Ahituv, Nadav
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054837/
https://ncbi.nlm.nih.gov/pubmed/23867016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-7-r72
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