Suppression of Spermatogenesis by Bisdichloroacetyldiamines Is Mediated by Inhibition of Testicular Retinoic Acid Biosynthesis

The bisdichloroacetyldiamine WIN 18,446 reversibly inhibits spermatogenesis in many species, including humans; however, the mechanism by which WIN 18,446 functions is unknown. As retinoic acid is essential for spermatogenesis, we hypothesized that WIN 18,446 might inhibit retinoic acid biosynthesis...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Amory, John K., Muller, Charles H., Shimshoni, Jakob A., Isoherranen, Nina, Paik, Jisun, Moreb, Jan S., Amory, David W., Evanoff, Ryan, Goldstein, Alex S., Griswold, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370679/
https://ncbi.nlm.nih.gov/pubmed/20705791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2164/jandrol.110.010751
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares