Suppression of Spermatogenesis by Bisdichloroacetyldiamines Is Mediated by Inhibition of Testicular Retinoic Acid Biosynthesis

The bisdichloroacetyldiamine WIN 18,446 reversibly inhibits spermatogenesis in many species, including humans; however, the mechanism by which WIN 18,446 functions is unknown. As retinoic acid is essential for spermatogenesis, we hypothesized that WIN 18,446 might inhibit retinoic acid biosynthesis...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Amory, John K., Muller, Charles H., Shimshoni, Jakob A., Isoherranen, Nina, Paik, Jisun, Moreb, Jan S., Amory, David W., Evanoff, Ryan, Goldstein, Alex S., Griswold, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370679/
https://ncbi.nlm.nih.gov/pubmed/20705791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2164/jandrol.110.010751
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi