Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations

Retinoic acid (RA), the active metabolite of vitamin A, is required for spermatogenesis and many other biological processes. RA formation requires irreversible oxidation of retinal to RA by aldehyde dehydrogenase enzymes of the 1A family (ALDH1A). While ALDH1A1, ALDH1A2, and ALDH1A3 all form RA, the...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Arnold, Samuel L., Kent, Travis, Hogarth, Cathryn A., Schlatt, Stefan, Prasad, Bhagwat, Haenisch, Michael, Walsh, Thomas, Muller, Charles H., Griswold, Michael D., Amory, John K., Isoherranen, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306688/
https://ncbi.nlm.nih.gov/pubmed/25502770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054718
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