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Characterization of Conformational Changes and Protein-Protein Interactions of Rod Photoreceptor Phosphodiesterase (PDE6)

As the central effector of visual transduction, the regulation of photoreceptor phosphodiesterase (PDE6) is controlled by both allosteric mechanisms and extrinsic binding partners. However, the conformational changes and interactions of PDE6 with known interacting proteins are poorly understood. Usi...

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Autori principali: Matte, Suzanne L., Laue, Thomas M., Cote, Rick H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370194/
https://ncbi.nlm.nih.gov/pubmed/22514270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.354647
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