Characterization of Non-Nitrocatechol Pan and Isoform Specific Catechol-O-methyltransferase Inhibitors and Substrates

[Image: see text] Reduced dopamine neurotransmission in the prefrontal cortex has been implicated as causal for the negative symptoms and cognitive deficit associated with schizophrenia; thus, a compound which selectively enhances dopamine neurotransmission in the prefrontal cortex may have therapeu...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Robinson, Ronald G., Smith, Sean M., Wolkenberg, Scott E., Kandebo, Monika, Yao, Lihang, Gibson, Christopher R., Harrison, Scott T., Polsky-Fisher, Stacey, Barrow, James C., Manley, Peter J., Mulhearn, James J., Nanda, Kausik K., Schubert, Jeffrey W., Trotter, B. Wesley, Zhao, Zhijian, Sanders, John M., Smith, Robert F., McLoughlin, Debra, Sharma, Sujata, Hall, Dawn L., Walker, Tiffany L., Kershner, Jennifer L., Bhandari, Neetesh, Hutson, Pete H., Sachs, Nancy A.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Chemical Society 2011
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369789/
https://ncbi.nlm.nih.gov/pubmed/22860182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200109w
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