Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors

Connexin-43 (Cx43), a gap junction protein involved in control of cell proliferation, differentiation and migration, has been suggested to have a role in hematopoiesis. Cx43 is highly expressed in osteoblasts and osteogenic progenitors (OB/P). To elucidate the biologic function of Cx43 in the hemato...

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Autors principals: Gonzalez-Nieto, Daniel, Li, Lina, Kohler, Anja, Ghiaur, Gabriel, Ishikawa, Eri, Sengupta, Amitava, Madhu, Malav, Arnett, Jorden L., Santho, Rebecca A., Dunn, Susan K., Fishman, Glenn I., Gutstein, David E., Civitelli, Roberto, Barrio, Luis C., Gunzer, Matthias, Cancelas, Jose A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369607/
https://ncbi.nlm.nih.gov/pubmed/22498741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-368506
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