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Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL–initiating cells
The characterization and targeting of Philadelphia chromosome positive (Ph(+)) acute lymphoblastic leukemia (ALL)–initiating cells remains unresolved. Expression of the polycomb protein Bmi1 is up-regulated in patients with advanced stages of chronic myelogenous leukemia (CML). We report that Bmi1 t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257014/ https://ncbi.nlm.nih.gov/pubmed/22101899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-359232 |
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