Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL–initiating cells

The characterization and targeting of Philadelphia chromosome positive (Ph(+)) acute lymphoblastic leukemia (ALL)–initiating cells remains unresolved. Expression of the polycomb protein Bmi1 is up-regulated in patients with advanced stages of chronic myelogenous leukemia (CML). We report that Bmi1 t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sengupta, Amitava, Ficker, Ashley M., Dunn, Susan K., Madhu, Malav, Cancelas, Jose A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2012
Pynciau:
Lymphoid Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257014/
https://ncbi.nlm.nih.gov/pubmed/22101899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-359232
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg