Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt

BACKGROUND: In Plasmodium falciparum, resistance to chloroquine (CQ) is conferred by a K to T mutation at amino acid position 76 (K76T) in the P. falciparum CQ transporter (PfCRT). To date, at least 15 pfcrt genotypes, which are represented by combinations of five amino acids at positions 72-76, hav...

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Библиографические подробности
Главные авторы: Takahashi, Nobuyuki, Tanabe, Kazuyuki, Tsukahara, Takahiro, Dzodzomenyo, Mawuli, Dysoley, Lek, Khamlome, Boualam, Sattabongkot, Jetsumon, Nakamura, Masatoshi, Sakurai, Miki, Kobayashi, Jun, Kaneko, Akira, Endo, Hiroyoshi, Hombhanje, Francis, Tsuboi, Takafumi, Mita, Toshihiro
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369212/
https://ncbi.nlm.nih.gov/pubmed/22453078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-92
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