Limited Geographical Origin and Global Spread of Sulfadoxine-Resistant dhps Alleles in Plasmodium falciparum Populations

Background. Plasmodium falciparum malaria resistant to chloroquine and pyrimethamine originated in limited foci and migrated to Africa. It remains unresolved whether P. falciparum resistance to sulfadoxine, which is conferred by mutations in dihydropteroate synthase (DHPS), evolved following a simil...

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Bibliographische Detailangaben
Hauptverfasser: Mita, Toshihiro, Venkatesan, Meera, Ohashi, Jun, Culleton, Richard, Takahashi, Nobuyuki, Tsukahara, Takahiro, Ndounga, Mathieu, Dysoley, Lek, Endo, Hiroyoshi, Hombhanje, Francis, Ferreira, Marcelo U., Plowe, Christopher V., Tanabe, Kazuyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
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Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209816/
https://ncbi.nlm.nih.gov/pubmed/22021623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir664
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