Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt

BACKGROUND: In Plasmodium falciparum, resistance to chloroquine (CQ) is conferred by a K to T mutation at amino acid position 76 (K76T) in the P. falciparum CQ transporter (PfCRT). To date, at least 15 pfcrt genotypes, which are represented by combinations of five amino acids at positions 72-76, hav...

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Autors principals: Takahashi, Nobuyuki, Tanabe, Kazuyuki, Tsukahara, Takahiro, Dzodzomenyo, Mawuli, Dysoley, Lek, Khamlome, Boualam, Sattabongkot, Jetsumon, Nakamura, Masatoshi, Sakurai, Miki, Kobayashi, Jun, Kaneko, Akira, Endo, Hiroyoshi, Hombhanje, Francis, Tsuboi, Takafumi, Mita, Toshihiro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369212/
https://ncbi.nlm.nih.gov/pubmed/22453078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-92
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