Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt

BACKGROUND: In Plasmodium falciparum, resistance to chloroquine (CQ) is conferred by a K to T mutation at amino acid position 76 (K76T) in the P. falciparum CQ transporter (PfCRT). To date, at least 15 pfcrt genotypes, which are represented by combinations of five amino acids at positions 72-76, hav...

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Hauptverfasser: Takahashi, Nobuyuki, Tanabe, Kazuyuki, Tsukahara, Takahiro, Dzodzomenyo, Mawuli, Dysoley, Lek, Khamlome, Boualam, Sattabongkot, Jetsumon, Nakamura, Masatoshi, Sakurai, Miki, Kobayashi, Jun, Kaneko, Akira, Endo, Hiroyoshi, Hombhanje, Francis, Tsuboi, Takafumi, Mita, Toshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369212/
https://ncbi.nlm.nih.gov/pubmed/22453078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-92
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