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Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt
BACKGROUND: In Plasmodium falciparum, resistance to chloroquine (CQ) is conferred by a K to T mutation at amino acid position 76 (K76T) in the P. falciparum CQ transporter (PfCRT). To date, at least 15 pfcrt genotypes, which are represented by combinations of five amino acids at positions 72-76, hav...
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| Auteurs principaux: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369212/ https://ncbi.nlm.nih.gov/pubmed/22453078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-92 |
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