Little Polymorphism at the K13 Propeller Locus in Worldwide Plasmodium falciparum Populations Prior to the Introduction of Artemisinin Combination Therapies

The emergence and spread of artemisinin-resistant Plasmodium falciparum is of huge concern for the global effort toward malaria control and elimination. Artemisinin resistance, defined as a delayed time to parasite clearance following administration of artemisinin, is associated with mutations in th...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Mita, Toshihiro, Culleton, Richard, Takahashi, Nobuyuki, Nakamura, Masatoshi, Tsukahara, Takahiro, Hunja, Carol W., Win, Zin Zayar, Htike, Wah Win, Marma, Aung S., Dysoley, Lek, Ndounga, Mathieu, Dzodzomenyo, Mawuli, Akhwale, Willis S., Kobayashi, Jun, Uemura, Haruki, Kaneko, Akira, Hombhanje, Francis, Ferreira, Marcelo U., Björkman, Anders, Endo, Hiroyoshi, Ohashi, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Epidemiology and Surveillance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879392/
https://ncbi.nlm.nih.gov/pubmed/27001814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02370-15
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