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DNA Sequence Variants in the Carbonyl Reductase 1 Gene (cbr1) in 7 Breeds of Canis Lupus Familiaris
The anticancer anthracyclines doxorubicin and daunorubicin are used to treat a variety of cancers in dogs. The therapeutic utility of anthracyclines is limited by the development of cardiotoxicity in some cases. The synthesis of anthracycline alcohol metabolites by carbonyl reductase 1 (CBR1) is cru...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368598/ https://ncbi.nlm.nih.gov/pubmed/22614280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4238/2012.April.27.10 |
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