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Selective blockade of microRNA processing by Lin-28

MicroRNAs (miRNAs) play critical roles in development, and dysregulation of miRNA expression has been observed in human malignancies. Recent evidence suggests that the processing of several primary miRNA transcripts (pri-miRNAs) is blocked post-transcriptionally in embryonic stem (ES) cells, embryon...

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Bibliografiska uppgifter
Huvudupphovsmän: Viswanathan, Srinivas R., Daley, George Q., Gregory, Richard I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368499/
https://ncbi.nlm.nih.gov/pubmed/18292307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1154040
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