The C-Terminus of Troponin T Is Essential for Maintaining the Inactive State of Regulated Actin

Striated muscle contraction is regulated by the actin binding proteins tropomyosin and troponin. Defects in these proteins lead to myopathies and cardiomyopathies. Deletion of the 14 C-terminal residues of cardiac troponin T leads to hypertrophic cardiomyopathy. We showed earlier that regulated acti...

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Bibliografiska uppgifter
Huvudupphovsmän: Franklin, Andrew J., Baxley, Tamatha, Kobayashi, Tomoyoshi, Chalovich, Joseph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2012
Ämnen:
Muscle, Motility, and Motor Proteins
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368147/
https://ncbi.nlm.nih.gov/pubmed/22713569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.037
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