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The C-Terminus of Troponin T Is Essential for Maintaining the Inactive State of Regulated Actin
Striated muscle contraction is regulated by the actin binding proteins tropomyosin and troponin. Defects in these proteins lead to myopathies and cardiomyopathies. Deletion of the 14 C-terminal residues of cardiac troponin T leads to hypertrophic cardiomyopathy. We showed earlier that regulated acti...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368147/ https://ncbi.nlm.nih.gov/pubmed/22713569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.037 |
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