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Troponin C Mutations Partially Stabilize the Active State of Regulated Actin and Fully Stabilize the Active State When Paired with Δ14 TnT
Striated muscle contraction is regulated by the actin-associated proteins tropomyosin and troponin. The extent of activation of myosin ATPase activity is lowest in the absence of both Ca(2+) and activating cross-bridges (i.e., S1-ADP or rigor S1). Binding of activating species of myosin to actin at...
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| Publicado en: | Biochemistry |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448410/ https://ncbi.nlm.nih.gov/pubmed/28530094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01092 |
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