The C-Terminus of Troponin T Is Essential for Maintaining the Inactive State of Regulated Actin

Striated muscle contraction is regulated by the actin binding proteins tropomyosin and troponin. Defects in these proteins lead to myopathies and cardiomyopathies. Deletion of the 14 C-terminal residues of cardiac troponin T leads to hypertrophic cardiomyopathy. We showed earlier that regulated acti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Franklin, Andrew J., Baxley, Tamatha, Kobayashi, Tomoyoshi, Chalovich, Joseph M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2012
Gaiak:
Muscle, Motility, and Motor Proteins
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368147/
https://ncbi.nlm.nih.gov/pubmed/22713569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.037
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