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How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens?

Pathogens such as trypanosomes and malaria use antigenic variation to evade immune responses and prolong the duration of infections. As pathogens typically express more than one antigen, even relatively rare conserved antigens might be expected to trigger cross-reactive immune responses capable of c...

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Sonraí Bibleagrafaíochta
Main Authors: Johnson, Philip L. F., Kochin, Beth F., Ahmed, Rafi, Antia, Rustom
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Royal Society 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367775/
https://ncbi.nlm.nih.gov/pubmed/22438498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.0005
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