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How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens?
Pathogens such as trypanosomes and malaria use antigenic variation to evade immune responses and prolong the duration of infections. As pathogens typically express more than one antigen, even relatively rare conserved antigens might be expected to trigger cross-reactive immune responses capable of c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367775/ https://ncbi.nlm.nih.gov/pubmed/22438498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.0005 |
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