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Modulation of microRNA processing by mismatch repair protein MutLα

MicroRNAs (miRNAs) are critical post-transcriptional regulators and are derived from hairpin-shaped primary transcripts via a series of processing steps. However, how the production of individual miRNAs is regulated remains largely unknown. Similarly, loss or overexpression of the key mismatch repai...

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Détails bibliographiques
Auteurs principaux: Mao, Guogen, Lee, Sanghee, Ortega, Janice, Gu, Liya, Li, Guo-Min
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367530/
https://ncbi.nlm.nih.gov/pubmed/22290424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.18
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