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Mispair-bound human MutS–MutL complex triggers DNA incisions and activates mismatch repair
DNA mismatch repair (MMR) relies on MutS and MutL ATPases for mismatch recognition and strand-specific nuclease recruitment to remove mispaired bases in daughter strands. However, whether the MutS–MutL complex coordinates MMR by ATP-dependent sliding on DNA or protein–protein interactions between th...
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| Publicado en: | Cell Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer Singapore
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8089094/ https://ncbi.nlm.nih.gov/pubmed/33510387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-021-00468-y |
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