Učitavanje...

Mispair-bound human MutS–MutL complex triggers DNA incisions and activates mismatch repair

DNA mismatch repair (MMR) relies on MutS and MutL ATPases for mismatch recognition and strand-specific nuclease recruitment to remove mispaired bases in daughter strands. However, whether the MutS–MutL complex coordinates MMR by ATP-dependent sliding on DNA or protein–protein interactions between th...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cell Res
Glavni autori: Ortega, Janice, Lee, Grace Sanghee, Gu, Liya, Yang, Wei, Li, Guo-Min
Format: Artigo
Jezik:Inglês
Izdano: Springer Singapore 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089094/
https://ncbi.nlm.nih.gov/pubmed/33510387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-021-00468-y
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!