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Age-related aneuploidy through cohesion exhaustion
The trend of women to become pregnant when older than in previous generations poses a paramount medical problem, for oocytes are particularly prone to chromosome missegregation, and aneuploidy increases with age. Recent data strongly suggest that as oocyte age increases sister chromatid cohesion is...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367239/ https://ncbi.nlm.nih.gov/pubmed/22565322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.54 |
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