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Meiotic Origins of Maternal Age-Related Aneuploidy

Chromosome segregation errors in female meiosis lead to aneuploidy in the resulting egg and embryo, making them one of the leading genetic causes of spontaneous abortions and developmental disabilities in humans. It is known that aneuploidy of meiotic origin increases dramatically as women age, and...

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Detalhes bibliográficos
Main Authors: Chiang, Teresa, Schultz, Richard M., Lampson, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313661/
https://ncbi.nlm.nih.gov/pubmed/21957193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.094367
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