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Meiotic Origins of Maternal Age-Related Aneuploidy

Chromosome segregation errors in female meiosis lead to aneuploidy in the resulting egg and embryo, making them one of the leading genetic causes of spontaneous abortions and developmental disabilities in humans. It is known that aneuploidy of meiotic origin increases dramatically as women age, and...

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Hlavní autoři: Chiang, Teresa, Schultz, Richard M., Lampson, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for the Study of Reproduction, Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313661/
https://ncbi.nlm.nih.gov/pubmed/21957193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.094367
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