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Age-related aneuploidy through cohesion exhaustion

The trend of women to become pregnant when older than in previous generations poses a paramount medical problem, for oocytes are particularly prone to chromosome missegregation, and aneuploidy increases with age. Recent data strongly suggest that as oocyte age increases sister chromatid cohesion is...

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Detalhes bibliográficos
Autor principal: Jessberger, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367239/
https://ncbi.nlm.nih.gov/pubmed/22565322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.54
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