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The Nrf2-Inducible Antioxidant Defense in Astrocytes can be Both Up- and Down-Regulated by Activated Microglia: Involvement of p38 MAPK
The effects of microglia-conditioned medium (MCM) on the inducible Nrf2 system in astrocyte-rich cultures were investigated by determination of glutathione (GSH) levels, γglutamylcysteine ligase (γGCL) activity, the protein levels of Nrf2, Keap1, the modulatory subunit of γGCL (γGCL-M) and activated...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366915/ https://ncbi.nlm.nih.gov/pubmed/21351160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21151 |
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