Time-dependent effects of systemic lipopolysaccharide injection on regulators of antioxidant defense Nrf2 and PGC-1 α in neonatal rat brain.

BACKGROUND/AIMS: Both excitotoxicity and neuroinflammation are associated with oxidative stress. One transcription factor, Nrf2 and one transcription co-factor PGC-1α, increase the endogenous antioxidant defense and can thus modulate neuronal cell death. Here we have investigated the temporal effect...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Correa, Fernando, Ljunggren, Elin, Patil, Jaspal, Wang, Xiaoyang, Hagberg, Henrik, Mallard, Carina, Sandberg, Mats
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096332/
https://ncbi.nlm.nih.gov/pubmed/23635713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000347161
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