NRF2-regulation in brain health and disease: implication of cerebral inflammation

The nuclear factor erythroid 2 related factor 2 (NRF2) is a key regulator of endogenous inducible defense systems in the body. Under physiological conditions NRF2 is mainly located in the cytoplasm. However, in response to oxidative stress, NRF2 translocates to the nucleus and binds to specific DNA...

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Autores principales: Sandberg, Mats, Patil, Jaspal, D’Angelo, Barbara, Weber, Stephen G, Mallard, Carina
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958930/
https://ncbi.nlm.nih.gov/pubmed/24262633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.11.004
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https://ncbi.nlm.nih.gov/pmc/articles/PMC3958930/
https://ncbi.nlm.nih.gov/pubmed/24262633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.11.004