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Time-dependent effects of systemic lipopolysaccharide injection on regulators of antioxidant defense Nrf2 and PGC-1 α in neonatal rat brain.
BACKGROUND/AIMS: Both excitotoxicity and neuroinflammation are associated with oxidative stress. One transcription factor, Nrf2 and one transcription co-factor PGC-1α, increase the endogenous antioxidant defense and can thus modulate neuronal cell death. Here we have investigated the temporal effect...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096332/ https://ncbi.nlm.nih.gov/pubmed/23635713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000347161 |
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