Physical and Functional Interaction between Ribosomal Protein L11 and the Tumor Suppressor ARF

The ARF tumor suppressor protein activates p53 in response to oncogenic stress, whereas ribosomal protein L11 induces p53 following ribosomal stress. Both proteins bind to central, albeit non-overlapping, regions of MDM2 and suppress MDM2 activity toward p53. However, it is not known whether the two...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Dai, Mu-Shui, Challagundla, Kishore B., Sun, Xiao-Xin, Palam, Lakshmi Reddy, Zeng, Shelya X., Wek, Ronald C., Lu, Hua
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
Signal Transduction
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366788/
https://ncbi.nlm.nih.gov/pubmed/22467867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311902
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים