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Physical and Functional Interaction between Ribosomal Protein L11 and the Tumor Suppressor ARF
The ARF tumor suppressor protein activates p53 in response to oncogenic stress, whereas ribosomal protein L11 induces p53 following ribosomal stress. Both proteins bind to central, albeit non-overlapping, regions of MDM2 and suppress MDM2 activity toward p53. However, it is not known whether the two...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366788/ https://ncbi.nlm.nih.gov/pubmed/22467867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311902 |
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