Physical and Functional Interaction between Ribosomal Protein L11 and the Tumor Suppressor ARF

The ARF tumor suppressor protein activates p53 in response to oncogenic stress, whereas ribosomal protein L11 induces p53 following ribosomal stress. Both proteins bind to central, albeit non-overlapping, regions of MDM2 and suppress MDM2 activity toward p53. However, it is not known whether the two...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Dai, Mu-Shui, Challagundla, Kishore B., Sun, Xiao-Xin, Palam, Lakshmi Reddy, Zeng, Shelya X., Wek, Ronald C., Lu, Hua
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366788/
https://ncbi.nlm.nih.gov/pubmed/22467867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311902
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki