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Nucleostemin stabilizes ARF by inhibiting the ubiquitin ligase ULF
Up-regulated expression of nucleolar GTPase Nucleostemin (NS) has been associated with increased cellular proliferation potential and tumor malignancy during cancer development. Recent reports attribute the growth regulatory effects of NS protein to its role in facilitating ribosome production. Howe...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4212020/ https://ncbi.nlm.nih.gov/pubmed/24769896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.103 |
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