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Streptococcus uberis Plasminogen Activator (SUPA) Activates Human Plasminogen through Novel Species-specific and Fibrin-targeted Mechanisms

Bacterial plasminogen (Pg) activators generate plasmin to degrade fibrin blood clots and other proteins that modulate the pathogenesis of infection, yet despite strong homology between mammalian Pgs, the activity of bacterial Pg activators is thought to be restricted to the Pg of their host mammalia...

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Autors principals: Zhang, Yi, Gladysheva, Inna P., Houng, Aiilyan K., Reed, Guy L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365949/
https://ncbi.nlm.nih.gov/pubmed/22518846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359315
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