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Streptococcus uberis Plasminogen Activator (SUPA) Activates Human Plasminogen through Novel Species-specific and Fibrin-targeted Mechanisms

Bacterial plasminogen (Pg) activators generate plasmin to degrade fibrin blood clots and other proteins that modulate the pathogenesis of infection, yet despite strong homology between mammalian Pgs, the activity of bacterial Pg activators is thought to be restricted to the Pg of their host mammalia...

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Detalhes bibliográficos
Main Authors: Zhang, Yi, Gladysheva, Inna P., Houng, Aiilyan K., Reed, Guy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365949/
https://ncbi.nlm.nih.gov/pubmed/22518846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359315
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