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Acute Activation of β(2)-Adrenergic Receptor Regulates Focal Adhesions through βArrestin2- and p115RhoGEF Protein-mediated Activation of RhoA

β(2)-Adrenergic receptors (β(2)ARs) regulate cellular functions through G protein-transduced and βArrestin-transduced signals. β(2)ARs have been shown to regulate cancer cell migration, but the underlying mechanisms are not well understood. Here, we report that β(2)AR regulates formation of focal ad...

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Autori principali: Ma, Xiaojie, Zhao, Yu, Daaka, Yehia, Nie, Zhongzhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365927/
https://ncbi.nlm.nih.gov/pubmed/22500016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.352260
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