Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia

[Image: see text] Ectopic Mer expression promotes pro-survival signaling and contributes to leukemogenesis and chemoresistance in childhood acute lymphoblastic leukemia (ALL). Consequently, Mer kinase inhibitors may promote leukemic cell death and further act as chemosensitizers increasing efficacy...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Liu, Jing, Yang, Chao, Simpson, Catherine, DeRyckere, Deborah, Van Deusen, Amy, Miley, Michael J., Kireev, Dmitri, Norris-Drouin, Jacqueline, Sather, Susan, Hunter, Debra, Korboukh, Victoria K., Patel, Hari S., Janzen, William P., Machius, Mischa, Johnson, Gary L., Earp, H. Shelton, Graham, Douglas K., Frye, Stephen V., Wang, Xiaodong
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2012
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365829/
https://ncbi.nlm.nih.gov/pubmed/22662287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200239k
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker