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N-Glycosylation of TRPM8 Ion Channels Modulates Temperature Sensitivity of Cold Thermoreceptor Neurons

TRPM8 is a member of the transient receptor potential ion channel superfamily, which is expressed in sensory neurons and is activated by cold and cooling compounds, such as menthol. Activation of TRPM8 by agonists takes place through shifts in its voltage activation curve, allowing channel opening a...

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Autores principales: Pertusa, María, Madrid, Rodolfo, Morenilla-Palao, Cruz, Belmonte, Carlos, Viana, Félix
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365712/
https://ncbi.nlm.nih.gov/pubmed/22493431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312645
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