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Negative Modulation of TRPM8 Channel Function by Protein Kinase C in Trigeminal Cold Thermoreceptor Neurons

TRPM8 is the main molecular entity responsible for cold sensing. This polymodal ion channel is activated by cold, cooling compounds such as menthol, voltage, and rises in osmolality. In corneal cold thermoreceptor neurons (CTNs), TRPM8 expression determines not only their sensitivity to cold, but al...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Rivera, Bastián, Campos, Matías, Orio, Patricio, Madrid, Rodolfo, Pertusa, María
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352406/
https://ncbi.nlm.nih.gov/pubmed/32580281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124420
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