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Negative Modulation of TRPM8 Channel Function by Protein Kinase C in Trigeminal Cold Thermoreceptor Neurons

TRPM8 is the main molecular entity responsible for cold sensing. This polymodal ion channel is activated by cold, cooling compounds such as menthol, voltage, and rises in osmolality. In corneal cold thermoreceptor neurons (CTNs), TRPM8 expression determines not only their sensitivity to cold, but al...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Rivera, Bastián, Campos, Matías, Orio, Patricio, Madrid, Rodolfo, Pertusa, María
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352406/
https://ncbi.nlm.nih.gov/pubmed/32580281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124420
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