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Variable Threshold of Trigeminal Cold-Thermosensitive Neurons Is Determined by a Balance between TRPM8 and Kv1 Potassium Channels

Molecular determinants of threshold differences among cold thermoreceptors are unknown. Here we show that such differences correlate with the relative expression of I (KD), a current dependent on Shaker-like Kv1 channels that acts as an excitability brake, and I (TRPM8), a cold-activated excitatory...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Madrid, Rodolfo, de la Peña, Elvira, Donovan-Rodriguez, Tansy, Belmonte, Carlos, Viana, Félix
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666436/
https://ncbi.nlm.nih.gov/pubmed/19279249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4778-08.2009
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