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N-Glycosylation of TRPM8 Ion Channels Modulates Temperature Sensitivity of Cold Thermoreceptor Neurons

TRPM8 is a member of the transient receptor potential ion channel superfamily, which is expressed in sensory neurons and is activated by cold and cooling compounds, such as menthol. Activation of TRPM8 by agonists takes place through shifts in its voltage activation curve, allowing channel opening a...

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Détails bibliographiques
Auteurs principaux: Pertusa, María, Madrid, Rodolfo, Morenilla-Palao, Cruz, Belmonte, Carlos, Viana, Félix
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365712/
https://ncbi.nlm.nih.gov/pubmed/22493431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312645
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