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Reagentless Oxidative Folding of Disulfide-Rich Peptides is Catalyzed by an Intramolecular Diselenide
In cysteine-rich peptides, diselenides can be used as a proxy for disulfide bridges, since the energetic preference for diselenide bonding over mixed selenium-sulfur bonds simplifies folding. Herein we report that an intramolecular diselenide bond efficiently catalyzes the oxidative folding of selen...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365648/ https://ncbi.nlm.nih.gov/pubmed/22454362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201200062 |
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