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Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling
MutS protein recognizes mispaired bases in DNA and targets them for mismatch repair. Little is known about the transient conformations of MutS as it signals initiation of repair. We have used single-molecule fluorescence resonance energy transfer (FRET) measurements to report the conformational dyna...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365432/ https://ncbi.nlm.nih.gov/pubmed/22505031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.95 |
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