लोड हो रहा है...
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
The ubiquitin ligases RNF8 and RNF168 orchestrate DNA damage signalling through the ubiquitylation of histone H2A and the recruitment of downstream repair factors. Here, we demonstrate that RNF8, but not RNF168 or the canonical H2A ubiquitin ligase RNF2, mediates extensive chromatin decondensation....
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365417/ https://ncbi.nlm.nih.gov/pubmed/22531782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.104 |
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