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Junctate is a Ca(2)(+)-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)
Orai1 and stromal interaction molecule (STIM)1 are critical components of Ca(2+) release-activated Ca(2+) (CRAC) channels. Orai1 is a pore subunit of CRAC channels, and STIM1 acts as an endoplasmic reticulum (ER) Ca(2+) sensor that detects store depletion. Upon store depletion after T-cell receptor...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365170/ https://ncbi.nlm.nih.gov/pubmed/22586105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200667109 |
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