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Junctate is a Ca(2)(+)-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)

Orai1 and stromal interaction molecule (STIM)1 are critical components of Ca(2+) release-activated Ca(2+) (CRAC) channels. Orai1 is a pore subunit of CRAC channels, and STIM1 acts as an endoplasmic reticulum (ER) Ca(2+) sensor that detects store depletion. Upon store depletion after T-cell receptor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Srikanth, Sonal, Jew, Marcus, Kim, Kyun-Do, Yee, Ma-Khin, Abramson, Jeff, Gwack, Yousang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365170/
https://ncbi.nlm.nih.gov/pubmed/22586105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200667109
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