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STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects

BACKGROUND: Asthma is characterised by increased numbers of Th2-like cells in the airways and IgE secretion. Generation of Th2 cells requires interleukin (IL)-4 and IL-13 acting through their specific receptors and activating the transcription factor, signal transducer and activator of transcription...

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Autori principali: Tomita, Katsuyuki, Caramori, Gaetano, Ito, Kazuhiro, Sano, Hiroyuki, Lim, Sam, Oates, Timothy, Cosio, Borja, Chung, K Fan, Tohda, Yuji, Barnes, Peter J, Adcock, Ian M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364916/
https://ncbi.nlm.nih.gov/pubmed/22401596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-9-5
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